EXOC5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Exocyst complex component 5 is a protein that in humans is encoded by the EXOC5 gene.[5][6]

AliasesEXOC5, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P, exocyst complex component 5
End57,268,905 bp[1]
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EXOC5
Identifiers
AliasesEXOC5, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P, exocyst complex component 5
External IDsOMIM: 604469; MGI: 2145645; HomoloGene: 38195; GeneCards: EXOC5; OMA:EXOC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006544

NM_207214

RefSeq (protein)

NP_006535

NP_997097

Location (UCSC)Chr 14: 57.2 – 57.27 MbChr 14: 49.24 – 49.3 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.[6]

Interactions

EXOC5 has been shown to interact with Arf6.[7]

References

Further reading

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