FARP2

FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene.^[5][6][7]

PDBOrtholog search: PDBe RCSB

AliasesFARP2, FIR, FRG, PLEKHC3, FERM, ARH/RhoGEF and pleckstrin domain protein 2

External IDsOMIM: 617586; MGI: 2385126; HomoloGene: 8877; GeneCards: FARP2; OMA:FARP2 - orthologs

Chr.Chromosome 2 (human)^[1]

Quick facts Available structures, PDB ...

FARP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4GYV, 4GZU
Identifiers
Aliases	FARP2, FIR, FRG, PLEKHC3, FERM, ARH/RhoGEF and pleckstrin domain protein 2
External IDs	OMIM: 617586; MGI: 2385126; HomoloGene: 8877; GeneCards: FARP2; OMA:FARP2 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q37.3 Start 241,356,285 bp[1] End 241,494,841 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 D Start 93,439,801 bp[2] End 93,549,698 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon sural nerve right testis left testis right hemisphere of cerebellum skin of leg skin of abdomen rectum mucosa of sigmoid colon mucosa of transverse colon Top expressed in fossa calvaria primary oocyte zygote retinal pigment epithelium left lobe of liver secondary oocyte epithelium of lens body of femur molar More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cytoskeletal protein binding guanyl-nucleotide exchange factor activity Cellular component cytosol cytoskeleton cytoplasm Biological process osteoclast differentiation neuron remodeling actin cytoskeleton reorganization regulation of integrin activation podosome assembly cell adhesion Rac protein signal transduction regulation of Rho protein signal transduction semaphorin-plexin signaling pathway hair cycle process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9855 227377 Ensembl ENSG00000006607 ENSMUSG00000034066 UniProt O94887 Q91VS8 RefSeq (mRNA) NM_001282983 NM_001282984 NM_014808 NM_145519 RefSeq (protein) NP_001269912 NP_001269913 NP_055623 NP_663494 Location (UCSC) Chr 2: 241.36 – 241.49 Mb Chr 1: 93.44 – 93.55 Mb PubMed search [3] [4]
Wikidata
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