Fenharmane

Fenharmane (INNTooltip International Nonproprietary Name), also known as 1-benzyl-1,2,3,4-tetrahydronorharmane, is a sedative and tranquilizer of the β-carboline family.^[1][2] It has been said to have actions similar to those of reserpine, a monoamine-depleting agent.^[3][4][5][6] The drug has been reported to induce symptoms of depression analogously to reserpine.^[7][8] Fenharmane was developed in Czechoslovakia in the late 1950s.^[3][2][9]

Other namesFenharman; Phenharman; Phenharmane; Fenoharman; Fenoharmane; Phenoharman; Phenoharmane; 1-Benzyl-1,2,3,4-tetrahydronorharmane; Benzyltetrahydronorharman

Drug classSedative; Tranquilizer; Reserpine-like agent

CAS Number

• 3851-30-7

PubChem CID

• 71167

Quick facts Clinical data, Other names ...

Fenharmane

Clinical data
Other names	Fenharman; Phenharman; Phenharmane; Fenoharman; Fenoharmane; Phenoharman; Phenoharmane; 1-Benzyl-1,2,3,4-tetrahydronorharmane; Benzyltetrahydronorharman
Drug class	Sedative; Tranquilizer; Reserpine-like agent
Identifiers
IUPAC name 1-benzyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
CAS Number	3851-30-7
PubChem CID	71167
ChemSpider	64307
UNII	9E96TNX6EZ
ChEMBL	ChEMBL323357
CompTox Dashboard (EPA)	DTXSID101043296
Chemical and physical data
Formula	C18H18N2
Molar mass	262.356 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CNC(C2=C1C3=CC=CC=C3N2)CC4=CC=CC=C4
InChI InChI=1S/C18H18N2/c1-2-6-13(7-3-1)12-17-18-15(10-11-19-17)14-8-4-5-9-16(14)20-18/h1-9,17,19-20H,10-12H2 Key:LHVNPTMRAQQPID-UHFFFAOYSA-N

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