NED-19

Trans-NED-19 is a drug which acts as a potent and selective antagonist of the endogenous calcium channel opener nicotinic acid adenine dinucleotide phosphate (NAADP), thereby reducing the normal NAADP-mediated calcium flux without blocking calcium channels directly. It is used in research into the functions of NAADP signalling inside many different cell types.^{[1][2][3][4][5][6][7][8]}

CAS Number

• 1354235-96-3

PubChem CID

• 1427628

ChemSpider

• 24604981

ChEBI

• CHEBI:138526

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NED-19

Identifiers
IUPAC name (1R,3S)-1-[3-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
CAS Number	1354235-96-3
PubChem CID	1427628
ChemSpider	24604981
ChEBI	CHEBI:138526
ChEMBL	ChEMBL1222013
CompTox Dashboard (EPA)	DTXSID501102307
Chemical and physical data
Formula	C30H31FN4O3
Molar mass	514.601 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=C(C=C(C=C1)[C@@H]2C3=C(C[C@H](N2)C(=O)O)C4=CC=CC=C4N3)CN5CCN(CC5)C6=CC=CC=C6F
InChI InChI=1S/C30H31FN4O3/c1-38-27-11-10-19(16-20(27)18-34-12-14-35(15-13-34)26-9-5-3-7-23(26)31)28-29-22(17-25(33-28)30(36)37)21-6-2-4-8-24(21)32-29/h2-11,16,25,28,32-33H,12-15,17-18H2,1H3,(H,36,37)/t25-,28+/m0/s1 Key:FUHCEERDBRGPQZ-LBNVMWSVSA-N

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