Ferroquine

Ferroquine is a synthetic compound related to chloroquine which acts as an antimalarial, and shows good activity against chloroquine-resistant strains.^[1] It contains an organometallic ferrocene ring which is unusual in pharmaceuticals,^[2][3][4] and while it was first reported in 1997,^[5] it has progressed slowly through clinical trials, with results from Phase II trials showing reasonable safety and efficacy, and further trials ongoing.^[6][7]

CAS Number

• 185055-67-8

PubChem CID

• 140118553

ChemSpider

• 34537134

UNII

• 8D81JS19ET

Quick facts Identifiers, CAS Number ...

Ferroquine

Identifiers
IUPAC name 7-chloro-N-({2-[(dimethylamino)methyl]ferrocenyl}methyl)quinolin-4-amine
CAS Number	185055-67-8
PubChem CID	140118553
ChemSpider	34537134
UNII	8D81JS19ET
CompTox Dashboard (EPA)	DTXSID00939922
ECHA InfoCard	100.208.008
Chemical and physical data
Formula	C23H24ClFeN3
Molar mass	433.76 g·mol−1
InChI InChI=1S/C18H19ClN3.C5H5.Fe/c1-22(2)12-14-5-3-4-13(14)11-21-17-8-9-20-18-10-15(19)6-7-16(17)18;1-2-4-5-3-1;/h3-10H,11-12H2,1-2H3,(H,20,21);1-5H;/q2*-1;+2 Key:DDENDDKMBDTHAX-UHFFFAOYSA-N

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