Fipexide

Fipexide
Clinical data
ATC code	N06BX05 (WHO) ;
Identifiers
	IUPAC name 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-; 2-(4-chlorophenoxy)ethanone;
CAS Number	34161-24-5 ;
PubChem CID	3351;
ChemSpider	3234 ;
UNII	TG44VME01D;
KEGG	D07345 ;
ChEMBL	ChEMBL254857 ;
CompTox Dashboard (EPA)	DTXSID5044657 ;
ECHA InfoCard	100.047.128
Chemical and physical data
Formula	C20H21ClN2O4
Molar mass	388.85 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc4ccc(OCC(=O)N1CCN(CC1)Cc2ccc3OCOc3c2)cc4;
	InChI InChI=1S/C20H21ClN2O4/c21-16-2-4-17(5-3-16)25-13-20(24)23-9-7-22(8-10-23)12-15-1-6-18-19(11-15)27-14-26-18/h1-6,11H,7-10,12-14H2 ; Key:BFUJHVVEMMWLHC-UHFFFAOYSA-N ;
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Fipexide (Attentil, Vigilor) is a psychoactive drug of the piperazine chemical class which was developed in Italy in 1983.^[1] It was used as a nootropic drug in Italy and France, mainly for the treatment of senile dementia,^[2] but is no longer in common use due to the occurrence of rare adverse drug reactions including fever^[3] and hepatitis. Fipexide is similar in action to other nootropic drugs such as piracetam^{[citation needed]} and has a few similarities in chemical structure to centrophenoxine. Chemically, it is an amide union of parachlorophenoxyacetate and methylenedioxybenzylpiperazine (MDBZP), and has been shown to metabolize to the latter, which plays a significant role in its effects^{[citation needed]}.

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