G-4 (drug)

G-4, also known as 3,4-tetramethylene-2,5-dimethoxyamphetamine or as 6-(2-aminopropyl)-5,8-dimethoxytetralin, is a chemical compound of the phenethylamine, amphetamine, and DOx families.^[1][2] It is one of several homologues of Ganesha (G).^[1][2]

Other namesG4; Ganesha-4; GANESHA-4; 3C-G-4; 3,4-Tetramethylene-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-(tetramethylene)amphetamine; 6-(2-Aminopropyl)-5,8-dimethoxytetralin; DOG-4

Routes of
administrationUnknown^[1]

ATC code

• None

Duration of actionUnknown^[1]

Quick facts Clinical data, Other names ...

G-4

Clinical data
Other names	G4; Ganesha-4; GANESHA-4; 3C-G-4; 3,4-Tetramethylene-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-(tetramethylene)amphetamine; 6-(2-Aminopropyl)-5,8-dimethoxytetralin; DOG-4
Routes of administration	Unknown[1]
ATC code	None
Pharmacokinetic data
Duration of action	Unknown[1]
Identifiers
IUPAC name 1-(1,4-dimethoxy-5,6,7,8-tetrahydronaphthalen-2-yl)propan-2-amine
PubChem CID	57465383
ChemSpider	76392985
Chemical and physical data
Formula	C15H23NO2
Molar mass	249.354 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC(=C2CCCCC2=C1OC)OC)N
InChI InChI=1S/C15H23NO2/c1-10(16)8-11-9-14(17-2)12-6-4-5-7-13(12)15(11)18-3/h9-10H,4-8,16H2,1-3H3 Key:SEIUSMPGGATKFD-UHFFFAOYSA-N

Close

In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists G-4's dose as unknown and its duration as unknown.^[1][2] He was unable to complete the last step of its chemical synthesis and did not test it or determine its properties and effects.^[1] The chemical synthesis of G-4 has been described.^[1]

G-4 was first described in the literature by Shulgin in PiHKAL in 1991.^[1] It is a controlled substance in Canada under phenethylamine blanket-ban language.^[3]