GBP5

GBP5
Identifiers
Aliases	GBP5, GBP-5, guanylate binding protein 5
External IDs	OMIM: 611467; MGI: 2429943; GeneCards: GBP5
Gene location (Human)
Chr.	Chromosome 1 (human)
End	89,272,860 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	142,228,105 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; appendix; ; monocyte; ; blood; ; lymph node; ; spleen; ; bone marrow cell; ; gallbladder; ; right uterine tube; ; testicle;
	Top expressed in
	spleen; ; urinary bladder; ; thymus; ; white adipose tissue; ; jejunum; ; ileum; ; quadriceps femoris muscle; ; bone marrow; ; islet of Langerhans; ; muscle tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; hydrolase activity; GTPase activity; identical protein binding; protein homodimerization activity;
Cellular component	cytoplasm; Golgi membrane; Golgi apparatus; membrane; cytoplasmic vesicle; perinuclear region of cytoplasm;
Biological process	immune system process; positive regulation of cytokine production involved in inflammatory response; inflammatory response; positive regulation of NLRP3 inflammasome complex assembly; protein homotetramerization; positive regulation of innate immune response; cellular response to interferon-gamma; response to bacterium; protein localization to Golgi apparatus;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	115362
	229898
	ENSG00000154451
	ENSMUSG00000105504
	Q96PP8
	Q8CFB4
	NM_052942; NM_001134486; NM_001391920
	NM_153564; NM_212440
	NP_001127958; NP_443174
	NP_705792
	Wikidata
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