GTF2H1

GTF2H1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1PFJ, 2DII, 2RNR, 2RUK, 2RVB
Identifiers
Aliases	GTF2H1, BTF2, P62, TFB1, TFIIH, general transcription factor IIH subunit 1
External IDs	OMIM: 189972; MGI: 1277216; HomoloGene: 3885; GeneCards: GTF2H1; OMA:GTF2H1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	18,367,045 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	46,473,224 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; endometrium; ; tonsil; ; right testis; ; left testis; ; monocyte; ; islet of Langerhans; ; smooth muscle tissue; ; gallbladder;
	Top expressed in
	spermatocyte; ; spermatid; ; yolk sac; ; Rostral migratory stream; ; lacrimal gland; ; genital tubercle; ; neural layer of retina; ; epiblast; ; morula; ; endothelial cell of lymphatic vessel;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; ATP-dependent activity, acting on DNA; chromatin binding; protein binding; RNA polymerase II CTD heptapeptide repeat kinase activity;
Cellular component	nucleoplasm; transcription factor TFIIH holo complex; nucleus; transcription factor TFIIH core complex;
Biological process	termination of RNA polymerase I transcription; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-templated; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; transcription, DNA-templated; cellular response to DNA damage stimulus; global genome nucleotide-excision repair; transcription-coupled nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; nucleotide-excision repair, DNA incision; DNA repair; positive regulation of transcription by RNA polymerase II; nucleotide-excision repair, preincision complex stabilization; nucleotide-excision repair; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; transcription by RNA polymerase I; phosphorylation of RNA polymerase II C-terminal domain; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision, 3'-to lesion; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
	2965
	14884
	ENSG00000110768; ENSG00000288114
	ENSMUSG00000006599
	P32780
	Q9DBA9
	NM_001142307; NM_005316
	NM_001291075; NM_008186; NM_001360075; NM_001360076
	NP_001135779; NP_005307
	NP_001278004; NP_032212; NP_001347004; NP_001347005
	Wikidata
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