H-151

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CAS Number
H-151
Identifiers
  • 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
ChEMBL
Chemical and physical data
FormulaC17H17N3O
Molar mass279.343 g·mol−1
3D model (JSmol)
  • CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32
  • InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)
  • Key:UJZDIKVQFMCLBE-UHFFFAOYSA-N

H-151 is an experimental drug which acts as an irreversible antagonist of the stimulator of interferon genes (STING) protein. It has antiinflammatory and antiviral effects by reducing cytokine signalling, and has potential application in numerous disease states in which inflammation plays a role.[1][2][3][4][5][6][7][8][9][10][11]

References

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