H-151

H-151
Identifiers
	IUPAC name 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea;
CAS Number	941987-60-6;
PubChem CID	7616033;
IUPHAR/BPS	10122;
ChemSpider	5932234;
ChEMBL	ChEMBL5179819;
Chemical and physical data
Formula	C17H17N3O
Molar mass	279.343 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32;
	InChI InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21); Key:UJZDIKVQFMCLBE-UHFFFAOYSA-N;

H-151 is an experimental drug which acts as an irreversible antagonist of the stimulator of interferon genes (STING) protein. It has antiinflammatory and antiviral effects by reducing cytokine signalling, and has potential application in numerous disease states in which inflammation plays a role.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]^[10]^[11]

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Identifiers

IUPAC name 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea
CAS Number	941987-60-6
PubChem CID	7616033
IUPHAR/BPS	10122
ChemSpider	5932234
ChEMBL	ChEMBL5179819
Chemical and physical data
Formula	C₁₇H₁₇N₃O
Molar mass	279.343 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32
InChI InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21) Key:UJZDIKVQFMCLBE-UHFFFAOYSA-N