SN-011

SN-011 is an experimental drug which acts as a potent antagonist of the stimulator of interferon genes (STING) protein. It binds with higher affinity to the cyclic dinucleotide binding pocket of STING than the endogenous activator 2'3'-cGAMP, and thereby prevents STING activation. SN-011 has antiinflammatory and antiviral effects by reducing cytokine signalling, and has potential application in numerous disease states in which inflammation plays a role.^{[1][2][3][4][5][6][7][8]}

CAS Number

• 2249435-90-1

PubChem CID

• 138005721

ChemSpider

• 71001485

ChEMBL

• ChEMBL5189857

Quick facts Identifiers, CAS Number ...

SN-011

Identifiers
IUPAC name N-[3-[(4-fluorophenyl)sulfonylamino]-4-hydroxyphenyl]-4-phenylbenzamide
CAS Number	2249435-90-1
PubChem CID	138005721
ChemSpider	71001485
ChEMBL	ChEMBL5189857
ECHA InfoCard	100.336.453
Chemical and physical data
Formula	C25H19FN2O4S
Molar mass	462.50 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)O)NS(=O)(=O)C4=CC=C(C=C4)F
InChI InChI=1S/C25H19FN2O4S/c26-20-10-13-22(14-11-20)33(31,32)28-23-16-21(12-15-24(23)29)27-25(30)19-8-6-18(7-9-19)17-4-2-1-3-5-17/h1-16,28-29H,(H,27,30) Key:GPXQUPCJIJBXHJ-UHFFFAOYSA-N

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