List of gene therapies
From Wikipedia, the free encyclopedia
This article contains a list of commercially available gene therapies.
- Alipogene tiparvovec (Glybera): AAV-based treatment for lipoprotein lipase deficiency (no longer commercially available)
- Axicabtagene ciloleucel (Yescarta): treatment for large B-cell lymphoma[1]
- Beremagene geperpavec (Vyjuvek): treatment of wounds.[2]
- Betibeglogene autotemcel (Zynteglo): treatment for beta thalassemia[3]
- Brexucabtagene autoleucel (Tecartus): treatment for mantle cell lymphoma and acute lymphoblastic leukemia[4][5]
- Cambiogenplasmid (Neovasculgen): treatment for vascular endothelial growth factor peripheral artery disease
- Ciltacabtagene autoleucel (Carvykti): treatment for multiple myeloma[6]
- Delandistrogene moxeparvovec (Elevidys): treatment for Duchenne muscular dystrophy[7][8]
- Elivaldogene autotemcel (Skysona): treatment for cerebral adrenoleukodystrophy[9]
- Etranacogene dezaparvovec (Hemgenix): AAV-based treatment for hemophilia B[10]
- Exagamglogene autotemcel (Casgevy): treatment for sickle cell disease.[11]
- Gendicine: treatment for head and neck squamous cell carcinoma
- Idecabtagene vicleucel (Abecma): treatment for multiple myeloma[12]
- Lovotibeglogene autotemcel (Lyfgenia): treatment for sickle cell disease.[11]
- Marnetegragene autotemcel (Kresladi): treatment of severe leukocyte adhesion deficiency type I.[13]
- Nadofaragene firadenovec (Adstiladrin): treatment for bladder cancer[14]
- Obecabtagene autoleucel (Aucatzyl): treatment of acute lymphoblastic leukemia[15][16]
- Onasemnogene abeparvovec (Zolgensma): AAV-based treatment for spinal muscular atrophy[17]
- Prademagene zamikeracel (Zevaskyn): recessive dystrophic epidermolysis bullosa[18]
- Revakinagene taroretcel (Encelto): treatment of macular telangiectasia type 2[19]
- Strimvelis: treatment for adenosine deaminase deficiency (ADA-SCID)
- Talimogene laherparepvec (Imlygic): treatment for melanoma in people who have recurring skin lesions[20]
- Tisagenlecleucel (Kymriah): treatment for B cell lymphoblastic leukemia[21]
- Valoctocogene roxaparvovec (Roctavian): treatment for hemophilia A[22][23][24]
- Voretigene neparvovec (Luxturna): AAV-based treatment for Leber congenital amaurosis[25]
