MNAT1

MNAT1
Identifiers
Aliases	MNAT1, CAP35, MAT1, RNF66, TFB3, CDK activating kinase assembly factor, MNAT1 component of CDK activating kinase
External IDs	OMIM: 602659; MGI: 106207; GeneCards: MNAT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1G25
Gene location (Human)
Chr.	Chromosome 14 (human)
End	60,969,965 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	73,320,762 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; muscle of thigh; ; gastrocnemius muscle; ; olfactory zone of nasal mucosa; ; ventricular zone; ; ganglionic eminence; ; popliteal artery; ; tibial arteries; ; right uterine tube; ; testicle;
	Top expressed in
	tail of embryo; ; epiblast; ; primitive streak; ; embryo; ; embryo; ; lens; ; genital tubercle; ; yolk sac; ; ventricular zone; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP-dependent activity, acting on DNA; protein N-terminus binding; metal ion binding; protein binding; RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin-dependent protein serine/threonine kinase activator activity; zinc ion binding;
Cellular component	nucleoplasm; nucleus; cytosol; transcription factor TFIIH holo complex; cyclin-dependent protein kinase activating kinase holoenzyme complex;
Biological process	termination of RNA polymerase I transcription; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription, DNA-templated; adult heart development; regulation of transcription by RNA polymerase II; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; negative regulation of apoptotic process; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; ventricular system development; transcription, DNA-templated; response to calcium ion; cell cycle; transcription-coupled nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; cell population proliferation; DNA repair; positive regulation of transcription by RNA polymerase II; positive regulation of smooth muscle cell proliferation; protein phosphorylation; nucleotide-excision repair, preincision complex assembly; positive regulation of cyclin-dependent protein serine/threonine kinase activity; nucleotide-excision repair; protein-containing complex assembly; G1/S transition of mitotic cell cycle; negative regulation of DNA helicase activity; G2/M transition of mitotic cell cycle; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	4331
	17420
	ENSG00000020426
	ENSMUSG00000021103
	P51948
	P51949
	NM_001177963; NM_002431
	NM_008612
	NP_001171434; NP_002422
	NP_032638
	Wikidata
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