Megasphaera
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Genus of bacteria
| Megasphaera | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Bacillota |
| Class: | Negativicutes |
| Order: | Veillonellales |
| Family: | Veillonellaceae |
| Genus: | Megasphaera Rogosa 1971 |
| Type species | |
| Megasphaera elsdenii (Gutierrez et al. 1959) Rogosa 1971[1] | |
| Species | |
Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes.[1][2] Several species in the genus, including M. elsdenii and M. hexanoica, are known to utilize lactate.[3]
This classification has been reexamined.[4] This genus appears to be a member of the Clostridia.
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[1] and National Center for Biotechnology Information (NCBI).[2]
| 16S rRNA based LTP_10_2024[5][6][7] | 120 marker proteins based GTDB 10-RS226[8][9][10] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Unassigned species:
- M. jansseni Heng et al. 2025
- "M. vaginalis" Srinivasan et al. 2021 non Bordigoni et al. 2020
See also
References
- 1 2 3 Megasphaera in LPSN; Freese, H. M.; Meier-Kolthoff, J. P.; Sardà Carbasse, J.; Afolayan, A. O.; Göker, M. (29 October 2025). "TYGS and LPSN in 2025: a Global Core Biodata Resource for genome-based classification and nomenclature of prokaryotes within DSMZ Digital Diversity". Nucleic Acids Research. 53: D1–D12. doi:10.1093/nar/gkaf1110.
- 1 2 Schoch CL; et al. "Megasphaera". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2025-06-05.
- ↑ Strachan, CR.; et al. (2025). "Distinct lactate utilization strategies drive niche differentiation between two co-existing Megasphaera species in the rumen microbiome". The ISME Journal. 19 (1) wraf147. doi:10.1093/ismejo/wraf147. PMC 12342382.
- ↑ Yutin N, Galperin MY (2013) A genomic update on Clostridial phylogeny: Gram-negative spore formers and other misplaced Clostridia. Environ Microbiol doi: 10.1111/1462-2920.12173
- ↑ "The LTP". Retrieved 10 December 2024.
- ↑ "LTP_all tree in newick format". Retrieved 10 December 2024.
- ↑ "LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
- ↑ "GTDB release 10-RS226". Genome Taxonomy Database. Retrieved 1 May 2025.
- ↑ "bac120_r226.sp_label". Genome Taxonomy Database. Retrieved 1 May 2025.
- ↑ "Taxon History". Genome Taxonomy Database. Retrieved 1 May 2025.
- Arik, H. D., Gulsen, N., Hayirli, A., & Alatas, M. S. (2019). Efficacy of Megasphaera elsdenii inoculation in subacute ruminal acidosis in cattle. Journal of animal physiology and animal nutrition, 103(2), 416–426.
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| Megasphaera |
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