Milameline

Chemical compound From Wikipedia, the free encyclopedia

Milameline (CI-979, PD-129,409, RU-35,926) is a non-selective muscarinic acetylcholine receptor partial agonist with cognition-acting properties that was being investigated for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued.[1]

  • Changing the O-methyl aldoxime to an O-propargyl oxime instead gives a separate molecule called RU 35986.[2]
ATC code
  • None
Quick facts Clinical data, ATC code ...
Milameline
Clinical data
ATC code
  • None
Identifiers
  • (E)-N-methoxy-1-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)methanimine
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.220.595 Edit this at Wikidata
Chemical and physical data
FormulaC8H14N2O
Molar mass154.213 g·mol−1
3D model (JSmol)
  • N(/OC)=C\C1=C\CCN(C)C1
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References

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