Milsaperidone
Medication
From Wikipedia, the free encyclopedia
Milsaperidone, sold under the brand name Bysanti, is an atypical antipsychotic used for the treatment of schizophrenia and bipolar disorder.[1][2] It is a prodrug of iloperidone and acts as a dopamine D2 receptor and serotonin 5-HT2A receptor antagonist, among other actions.[3][4] Milsaperidone was developed by Vanda Pharmaceuticals.
| Clinical data | |
|---|---|
| Trade names | Bysanti |
| Other names | VHX896, VHX-896 |
| AHFS/Drugs.com | bysanti |
| License data | |
| Routes of administration | Oral |
| Drug class | Atypical antipsychotic |
| ATC code |
|
| Legal status | |
| Legal status | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C24H29FN2O4 |
| Molar mass | 428.504 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Milsaperidone was approved for medical use in the United States in February 2026.[5]
Medical uses
Milsaperidone is indicated for the treatment of schizophrenia; and for the acute treatment of manic or mixed episodes associated with bipolar I disorder.[1]
Society and culture
Legal status
Milsaperidone was approved for medical use in the United States in February 2026.[6]
Names
Milsaperidone is the international nonproprietary name.
Milsaperidone is sold under the brand name Bysanti.[6]
Research
Milsaperidone is in phase III clinical trials for treatment of major depressive disorder.[7][8]