NDN (gene)

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Necdin is a protein that in humans is encoded by the NDN gene.[5][6]

AliasesNDN, HsT16328, PWCR, necdin, MAGE family member
End23,687,305 bp[1]
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NDN
Identifiers
AliasesNDN, HsT16328, PWCR, necdin, MAGE family member
External IDsOMIM: 602117; MGI: 97290; HomoloGene: 20559; GeneCards: NDN; OMA:NDN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002487

NM_010882

RefSeq (protein)

NP_002478

NP_035012

Location (UCSC)Chr 15: 23.69 – 23.69 MbChr 7: 62 – 62 Mb
PubMed search[3][4]
Wikidata
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Function

This intronless gene is located in the Prader–Willi syndrome (PWS) deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mice suggest that the protein encoded by this gene may suppress growth in postmitotic neurons.[6]

Necdin is used to stimulate growth regulation and DNA-dependent transcription regulation.[7]

Interactions

NDN (gene) has been shown to interact with:

References

Further reading

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