Orthohepadnavirus
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| Orthohepadnavirus | |
|---|---|
| TEM micrograph showing Hepatitis B virus virions | |
| Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Pararnavirae |
| Phylum: | Artverviricota |
| Class: | Revtraviricetes |
| Order: | Blubervirales |
| Family: | Hepadnaviridae |
| Genus: | Orthohepadnavirus |
| Species | |
|
See text | |
Orthohepadnavirus is a genus of viruses, in the family Hepadnaviridae.[1] Humans and other mammals serve as natural hosts. There are 19 species in this genus.[1] Diseases associated with this genus include: hepatitis, hepatocellular carcinoma (chronic infections), and cirrhosis.[1][2]
The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:[3]
- Orthohepadnavirus bassarisci, Ringtail hepatitis B virus
- Orthohepadnavirus equidae, Equid hepatitis B virus
- Orthohepadnavirus felisdomestici, Domestic cat hepatitis B virus
- Orthohepadnavirus hominoidei, Hepatitis B virus genotype D – includes HBV and ape-infecting relatives (chHBV, giHBV, goHBV, orHBV). Named after the Hominoidea.[4]
- Orthohepadnavirus lagothricis, Woolly monkey hepatitis B virus
- Orthohepadnavirus longidigiti, Long-fingered bat hepatitis B virus
- Orthohepadnavirus magniferrequini, Greater Horseshoe bat hepatitis B virus
- Orthohepadnavirus magnimyotis, Large myotis bat hepatitis B virus
- Orthohepadnavirus marmotae, Woodchuck hepatitis virus
- Orthohepadnavirus myominrhinus, Myodav bat hepatitis B virus
- Orthohepadnavirus philantombae, Tai Forest hepatitis B virus
- Orthohepadnavirus pomi, Pomona bat hepatitis B virus
- Orthohepadnavirus rotundifolii, Roundleaf bat hepatitis B virus – also includes HSBHBV
- Orthohepadnavirus sapaji, Capuchin monkey hepatitis B virus
- Orthohepadnavirus sciuri, Ground squirrel hepatitis virus (GSHV aka ASHV)
- Orthohepadnavirus soricicoronati, Crowned shrew hepatitis B virus
- Orthohepadnavirus soriciodoris, Musk shrew hepatitis B virus
- Orthohepadnavirus soricisinensis, Chinese shrew hepatitis B virus
- Orthohepadnavirus tabernarii, Tent-making bat hepatitis B virus
A few of the bat species were first reported in 2013.[5]
Structure
Viruses in the genus Orthohepadnavirus are enveloped, with spherical geometries, and T=4 symmetry. The diameter is around 42 nm. Genomes are circular, around 3.2kb in length. The genome codes for 7 proteins.[1][2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Orthohepadnavirus | Icosahedral | T=4 | Non-enveloped | Circular | Monopartite |