Oxalobacter paraformigenes
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| Oxalobacter paraformigenes | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Pseudomonadota |
| Class: | Betaproteobacteria |
| Order: | Burkholderiales |
| Family: | Oxalobacteraceae |
| Genus: | Oxalobacter |
| Species: | O. paraformigenes |
| Binomial name | |
| Oxalobacter paraformigenes Chmiel et al, 2022 | |
| Type strain | |
| Oxalobacter paraformigenes HOxBLST | |
Oxalobacter paraformigenes is a Gram negative, non-spore-forming, oxalate-degrading anaerobic bacterium that was first isolated from human fecal samples.[1] O. paraformigenes may have a role in calcium oxalate kidney stone disease because of its unique ability to utilize oxalate as its primary carbon source.[1]
Oxalobacter paraformigenes was originally thought to be a subgroup of Oxalobacter formigenes.[1] Based on fatty acid profile, 16S ribosomal RNA sequencing, and DNA probes specific to the oxc (oxalyl-CoA decarboxylase) gene and frc (formyl-CoA transferase), O. paraformigenes strain HOxBLS was considered a group II strain.[2][3][4][5] However, whole genome sequencing revealed that O. paraformigenes HOxBLS is a different species from O. formigenes and it was subsequently renamed.[6] The new species name paraformigenes uses the parent species formigenes and adds the Greek prefix para meaning "beside",[7] owing to that for the longest time O. paraformigenes was the only group II strain with a full genome sequence and it was used to make genetic comparisons between group I strains (now known as O. formigenes).[6]