PA-915

PA-915
Identifiers
	IUPAC name 1-(7-chloro-1H-indazol-3-yl)-N-[2-(1H-imidazol-5-yl)ethyl]-5-oxopyrrolidine-3-carboxamide;
CAS Number	2305204-24-2;
PubChem CID	142550469;
Chemical and physical data
Formula	C17H17ClN6O2
Molar mass	372.81 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C(CN(C1=O)C2=NNC3=C2C=CC=C3Cl)C(=O)NCCC4=CN=CN4;
	InChI InChI=1S/C17H17ClN6O2/c18-13-3-1-2-12-15(13)22-23-16(12)24-8-10(6-14(24)25)17(26)20-5-4-11-7-19-9-21-11/h1-3,7,9-10H,4-6,8H2,(H,19,21)(H,20,26)(H,22,23); Key:MCXQHNLGSHUYBL-UHFFFAOYSA-N;

PA-915 is a drug used in scientific research which acts as a selective antagonist of the pituitary adenylate cyclase-activating polypeptide type I receptor (PAC1). In animal studies it has been found to prevent the development of allodynia and shows analgesic effects against neuropathic pain,^[1] and also shows antidepressant effects.^[2]

FormulaC₁₇H₁₇ClN₆O₂

Molar mass372.81 g·mol⁻¹

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Identifiers

IUPAC name 1-(7-chloro-1H-indazol-3-yl)-N-[2-(1H-imidazol-5-yl)ethyl]-5-oxopyrrolidine-3-carboxamide
CAS Number	2305204-24-2
PubChem CID	142550469
Chemical and physical data
Formula	C₁₇H₁₇ClN₆O₂
Molar mass	372.81 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1C(CN(C1=O)C2=NNC3=C2C=CC=C3Cl)C(=O)NCCC4=CN=CN4
InChI InChI=1S/C17H17ClN6O2/c18-13-3-1-2-12-15(13)22-23-16(12)24-8-10(6-14(24)25)17(26)20-5-4-11-7-19-9-21-11/h1-3,7,9-10H,4-6,8H2,(H,19,21)(H,20,26)(H,22,23) Key:MCXQHNLGSHUYBL-UHFFFAOYSA-N