PACSIN1

PACSIN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3HAH, 3HAI, 3Q84, 3QNI
Identifiers
Aliases	PACSIN1, SDPI, protein kinase C and casein kinase substrate in neurons 1
External IDs	OMIM: 606512; MGI: 1345181; HomoloGene: 22674; GeneCards: PACSIN1; OMA:PACSIN1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	34,535,229 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	27,930,456 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; superior frontal gyrus; ; postcentral gyrus; ; entorhinal cortex; ; middle temporal gyrus; ; primary visual cortex; ; dorsolateral prefrontal cortex; ; anterior cingulate cortex; ; right hemisphere of cerebellum; ; prefrontal cortex;
	Top expressed in
	pontine nuclei; ; piriform cortex; ; superior frontal gyrus; ; primary visual cortex; ; subiculum; ; dorsal tegmental nucleus; ; cerebellar cortex; ; neural layer of retina; ; primary motor cortex; ; prefrontal cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytoskeletal protein binding; protein binding; phospholipid binding; lipid binding; identical protein binding;
Cellular component	cytoplasm; axon terminus; cytosol; endosome; cell projection; membrane; myelin sheath; plasma membrane; synapse; ruffle membrane; cell junction; perinuclear region of cytoplasm; neuron projection; cytoplasmic vesicle membrane; cytoplasmic vesicle; COPI-coated vesicle; cytoskeleton; photoreceptor ribbon synapse; presynaptic endocytic zone;
Biological process	regulation of endocytosis; negative regulation of endocytosis; protein localization to membrane; neuron projection morphogenesis; endocytosis; actin filament organization; neuron development; positive regulation of dendrite development; plasma membrane tubulation; synaptic vesicle endocytosis; protein localization to plasma membrane; cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	29993
	23969
	ENSG00000124507
	ENSMUSG00000040276
	Q9BY11
	Q61644
	NM_001199583; NM_020804
	NM_001286743; NM_001286744; NM_011861; NM_178365
	NP_001186512; NP_065855
	NP_001273672; NP_001273673; NP_035991; NP_848142
	Wikidata
View/Edit Human	View/Edit Mouse

Protein kinase C and casein kinase substrate in neurons protein 1 also known as syndapin I^[5]^[6] is an enzyme that in humans is encoded by the PACSIN1 gene.^[7]