POLR2J

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

DNA-directed RNA polymerase II subunit RPB11-a is an enzyme that in humans is encoded by the POLR2J gene.

PDBOrtholog search: PDBe RCSB
AliasesPOLR2J, POLR2J1, RPB11, RPB11A, RPB11m, hRPB14, polymerase (RNA) II subunit J, RNA polymerase II subunit J
Quick facts Available structures, PDB ...
POLR2J
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPOLR2J, POLR2J1, RPB11, RPB11A, RPB11m, hRPB14, polymerase (RNA) II subunit J, RNA polymerase II subunit J
External IDsOMIM: 604150; MGI: 109582; HomoloGene: 4542; GeneCards: POLR2J; OMA:POLR2J - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006234
NM_001371100
NM_001393919

NM_011293

RefSeq (protein)

NP_006225
NP_001358029

n/a

Location (UCSC)Chr 7: 102.47 – 102.48 MbChr 5: 136.15 – 136.15 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.[5]

Interactions

References

Further reading

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