POLR2L

POLR2L
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5FLM, 5IYD, 5IYC, 5IY8, 5IYA, 5IYB, 5IY6, 5IY9, 5IY7
Identifiers
Aliases	POLR2L, RBP10, RPABC5, RPB10, RPB10beta, RPB7.6, hRPB7.6, polymerase (RNA) II subunit L, RNA polymerase II subunit L, RNA polymerase II, I and III subunit L
External IDs	OMIM: 601189; MGI: 1913741; HomoloGene: 129854; GeneCards: POLR2L; OMA:POLR2L - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	842,529 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,055,045 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right ventricle; ; left ventricle; ; right auricle of heart; ; myocardium of left ventricle; ; abdominal fat; ; mucosa of transverse colon; ; biceps brachii; ; right adrenal gland; ; body of pancreas;
	Top expressed in
	morula; ; embryo; ; proximal tubule; ; embryo; ; adrenal gland; ; right kidney; ; lens; ; bone marrow; ; yolk sac; ; muscle of thigh;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; zinc ion binding; RNA polymerase II activity; metal ion binding; RNA polymerase III activity; DNA-directed 5'-3' RNA polymerase activity; protein binding; RNA polymerase I activity;
Cellular component	cytosol; nucleoplasm; RNA polymerase I complex; RNA polymerase III complex; RNA polymerase II, core complex; nucleus;
Biological process	termination of RNA polymerase I transcription; mRNA splicing, via spliceosome; epigenetic maintenance of chromatin in transcription-competent conformation; regulation of transcription by RNA polymerase I; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; transcription-coupled nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; fibroblast growth factor receptor signaling pathway; transcription by RNA polymerase III; snRNA transcription by RNA polymerase II; RNA metabolic process; regulation of gene silencing by miRNA; transcription, DNA-templated; transcription elongation from RNA polymerase I promoter; positive regulation of type I interferon production; somatic stem cell population maintenance; positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologs
	5441
	66491
	ENSG00000177700
	ENSMUSG00000038489
	P62875
	P62876
	NM_021128
	NM_025593
	NP_066951
	NP_079869
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene.^[5]

PDBOrtholog search: PDBe RCSB

AliasesPOLR2L, RBP10, RPABC5, RPB10, RPB10beta, RPB7.6, hRPB7.6, polymerase (RNA) II subunit L, RNA polymerase II subunit L, RNA polymerase II, I and III subunit L

External IDsOMIM: 601189; MGI: 1913741; HomoloGene: 129854; GeneCards: POLR2L; OMA:POLR2L - orthologs

Chr.Chromosome 11 (human)^[1]

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[1]

[2]

[3]

[4]

POLR2L

Function

Interactions

References

Further reading

Related Articles

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