Quazinone

Quazinone
Clinical data
Other names	Ro 13-6438
Routes of; administration	Oral
ATC code	None;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (3R)-6-Chloro-3-methyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one;
CAS Number	70018-51-8;
PubChem CID	6603980;
ChemSpider	5036286;
UNII	D1Q7F6C2FP;
KEGG	D05668;
CompTox Dashboard (EPA)	DTXSID6045795 ;
Chemical and physical data
Formula	C11H10ClN3O
Molar mass	235.67 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1cccc3c1CN2/C(=N\C(=O)[C@H]2C)N3;

Other namesRo 13-6438

Routes of
administrationOral

ATC code

None

Legal status

In general: ℞ (Prescription only)

Quazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease.^[1]^[2]^[3]^[4]^[5] It acts as a selective PDE3 inhibitor.^[6]^[7] It is no longer available.^[1]

[1]

[2]

[3]

[4]

[5]

[6]

[7]

v t e Phosphodiesterase inhibitors
PDE1	MMPX SCH-51866 Vinpocetine
PDE2	BAY 60-7550 Carbazeran EHNA Oxindole PDP
PDE3	Adibendan Amrinone (inamrinone) Anagrelide Benafentrine Bucladesine Carbazeran Cilostamide Cilostazol Enoximone Ensifentrine Imazodan KMUP-1 Meribendan Milrinone Olprinone Parogrelil Pimobendan Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine
PDE4	Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466 Cilomilast Cipamfylline Crisaborole Denbutylline Difamilast Drotaverine Ensifentrine Etazolate Filaminast Glaucine HT-0712 ICI-63197 Indimilast Irsogladine Lavamilast Lirimilast Lotamilast Luteolin Mesembrenone Mesembrine Mesopram Oglemilast Piclamilast Pumafentrine Revamilast Ro 20-1724 Roflumilast Rolipram Ronomilast RPL-554 RS-25344 Tetomilast Tofimilast YM-976 Zardaverine
PDE5	Acetildenafil Aildenafil Avanafil Beminafil Benzamidenafil Dasantafil Icariin Gisadenafil Homosildenafil Lodenafil Mirodenafil MY-5445 Nitrosoprodenafil Norcarbodenafil SCH-51866 Sildenafil Sulfoaildenafil T-0156 Tadalafil Udenafil Vardenafil
PDE7	BRL-50481
PDE9	BAY 73-6691 PF-04447943 Paraxanthine
PDE10	Balipodect Mardepodect MK-8189 Papaverine TC-E 5005 Tofisopam
PDE11	BC11-38
Non-selective	Aminophylline Caffeine Choline theophyllinate CPX Dipyridamole Doxofylline Enprofylline Ibudilast IBMX Luteolin Pentoxifylline Propentofylline Theobromine Theophylline Zaprinast
Unsorted	Diazepam Diprophylline DPCPX Furafylline Lisofylline MDL-12330A Moxaverine Oxagrelate Pentifylline Proxyphylline Quercetin Satigrel Tolafentrine Trapidil
See also: Receptor/signaling modulators

Quazinone

References

External links

Related Articles

Clinical data

Other names	Ro 13-6438
Routes of administration	Oral
ATC code	None
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (3R)-6-Chloro-3-methyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one
CAS Number	70018-51-8
PubChem CID	6603980
ChemSpider	5036286
UNII	D1Q7F6C2FP
KEGG	D05668
CompTox Dashboard (EPA)	DTXSID6045795
Chemical and physical data
Formula	C₁₁H₁₀ClN₃O
Molar mass	235.67 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1cccc3c1CN2/C(=N\C(=O)[C@H]2C)N3