R6372

R6372
Identifiers
	IUPAC name 8-[1-(4-methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;
CAS Number	2940-60-5;
PubChem CID	200932;
ChemSpider	173957;
Chemical and physical data
Formula	C22H27N3O
Molar mass	349.478 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC=C(C=C1)C(C)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4;
	InChI InChI=1S/C22H27N3O/c1-17-8-10-19(11-9-17)18(2)24-14-12-22(13-15-24)21(26)23-16-25(22)20-6-4-3-5-7-20/h3-11,18H,12-16H2,1-2H3,(H,23,26); Key:MBCUBRXUURKNCY-UHFFFAOYSA-N;

R6372 is a potent opioid analgesic drug from the spiropiperidine family, related to opioid designer drugs such as spirochlorphine. It has around 186x the potency of morphine, making it approximately twice the potency of fentanyl.^[1]

CAS Number

2940-60-5

PubChem CID

200932

ChemSpider

173957

FormulaC₂₂H₂₇N₃O

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R6372

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Identifiers

IUPAC name 8-[1-(4-methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
CAS Number	2940-60-5
PubChem CID	200932
ChemSpider	173957
Chemical and physical data
Formula	C₂₂H₂₇N₃O
Molar mass	349.478 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=CC=C(C=C1)C(C)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4
InChI InChI=1S/C22H27N3O/c1-17-8-10-19(11-9-17)18(2)24-14-12-22(13-15-24)21(26)23-16-25(22)20-6-4-3-5-7-20/h3-11,18H,12-16H2,1-2H3,(H,23,26) Key:MBCUBRXUURKNCY-UHFFFAOYSA-N