RAB5A
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.[5][6]
External IDsOMIM: 179512; MGI: 105926; HomoloGene: 68142; GeneCards: RAB5A; OMA:RAB5A - orthologs
Function
RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to early endosomes.[7] It drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles.[8]