RAB5A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesRAB5A, RAB5, member RAS oncogene family
Quick facts Available structures, PDB ...
RAB5A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRAB5A, RAB5, member RAS oncogene family
External IDsOMIM: 179512; MGI: 105926; HomoloGene: 68142; GeneCards: RAB5A; OMA:RAB5A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004162
NM_001292048

NM_025887

RefSeq (protein)

NP_001278977
NP_004153

NP_080163

Location (UCSC)Chr 3: 19.95 – 19.99 MbChr 17: 53.79 – 53.81 Mb
PubMed search[3][4]
Wikidata
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Function

RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to early endosomes.[7] It drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles.[8]

Interactions

RAB5A has been shown to interact with:

References

Further reading

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