RABEP1

Rab GTPase-binding effector protein 1 is an enzyme that in humans is encoded by the RABEP1 gene.^[5][6] It belongs to rabaptin protein family.

AliasesRABEP1, RAB5EP, RABPT5, rabaptin, RAB GTPase binding effector protein 1

External IDsOMIM: 603616; MGI: 1860236; GeneCards: RABEP1

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 17 (human)^[1]

Quick facts Identifiers, Aliases ...

RABEP1
Identifiers
Aliases	RABEP1, RAB5EP, RABPT5, rabaptin, RAB GTPase binding effector protein 1
External IDs	OMIM: 603616; MGI: 1860236; GeneCards: RABEP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1P4U, 1TU3, 1X79, 4N3Y, 4N3Z, 4Q9U
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.2 Start 5,282,265 bp[1] End 5,386,340 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3- B4|11 43.21 cM Start 70,735,604 bp[2] End 70,833,931 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of rectus abdominis Achilles tendon biceps brachii sural nerve postcentral gyrus internal globus pallidus C1 segment Skeletal muscle tissue of biceps brachii gastrocnemius muscle middle temporal gyrus Top expressed in dentate gyrus of hippocampal formation granule cell tail of embryo substantia nigra barrel cortex adrenal gland genital tubercle superior frontal gyrus sciatic nerve Region I of hippocampus proper primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function growth factor activity protein homodimerization activity protein binding GTPase activator activity protein domain specific binding Cellular component intracellular membrane-bounded organelle cytoplasmic vesicle endocytic vesicle cytoplasm recycling endosome endosome early endosome early endosome membrane protein-containing complex Biological process membrane fusion apoptotic process protein transport positive regulation of GTPase activity vesicle-mediated transport endocytosis regulation of signaling receptor activity Golgi to plasma membrane transport protein localization to ciliary membrane signal transduction Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 9135 54189 Ensembl ENSG00000029725 ENSMUSG00000020817 UniProt Q15276 O35551 RefSeq (mRNA) NM_001083585 NM_001291581 NM_001291582 NM_004703 NM_001291141 NM_001291142 NM_001291143 NM_019400 RefSeq (protein) NP_001077054 NP_001278510 NP_001278511 NP_004694 NP_001278070 NP_001278071 NP_001278072 NP_062273 Location (UCSC) Chr 17: 5.28 – 5.39 Mb Chr 11: 70.74 – 70.83 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close