RUFY1

RUFY1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YQM, 2YW8
Identifiers
Aliases	RUFY1, RABIP4, ZFYVE12, RUN and FYVE domain containing 1
External IDs	OMIM: 610327; MGI: 2429762; HomoloGene: 23522; GeneCards: RUFY1; OMA:RUFY1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	179,610,012 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	50,321,952 bp
RNA expression pattern
	Top expressed in
	monocyte; ; Achilles tendon; ; sural nerve; ; corpus callosum; ; ventricular zone; ; blood; ; right uterine tube; ; gastric mucosa; ; granulocyte; ; skin of leg;
	Top expressed in
	primary oocyte; ; neural layer of retina; ; right kidney; ; granulocyte; ; muscle of thigh; ; zygote; ; transitional epithelium of urinary bladder; ; proximal tubule; ; retinal pigment epithelium; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; lipid binding; SH3 domain binding; SH2 domain binding;
Cellular component	intracellular membrane-bounded organelle; membrane; cytoplasm; cytosol; nuclear speck; early endosome membrane; endosome; nucleus;
Biological process	protein transport; endocytosis; phosphatidylinositol biosynthetic process; regulation of endocytosis; small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	80230
	216724
	ENSG00000284260; ENSG00000176783
	ENSMUSG00000020375
	Q96T51
	Q8BIJ7
	NM_001040451; NM_001040452; NM_025158
	NM_172557
	NP_001035541; NP_001035542; NP_079434
	NP_766145
	Wikidata
View/Edit Human	View/Edit Mouse

RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene.^[5]^[6] It is named after the RUN and FYVE domains it contains.