BMX (gene)

BMX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EKX, 2YS2, 3SXR, 3SXS
Identifiers
Aliases	BMX, ETK, PSCTK2, PSCTK3, BMX non-receptor tyrosine kinase
External IDs	OMIM: 300101; MGI: 1101778; HomoloGene: 20411; GeneCards: BMX; OMA:BMX - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	15,556,529 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	163,041,189 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; right auricle of heart; ; bone marrow; ; cardiac muscle tissue of right atrium; ; testicle; ; right coronary artery; ; subcutaneous adipose tissue; ; right lung; ; Achilles tendon; ; urethra;
	Top expressed in
	granulocyte; ; atrioventricular valve; ; atrium; ; lumbar spinal ganglion; ; tunica media of zone of aorta; ; zygote; ; tibiofemoral joint; ; endocardial cushion; ; right lung lobe; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; signal transducer activity; metal ion binding; kinase activity; protein binding; protein tyrosine kinase activity; signaling receptor binding; ATP binding; non-membrane spanning protein tyrosine kinase activity;
Cellular component	cytoplasm; cytosol; extrinsic component of cytoplasmic side of plasma membrane; ruffle membrane; nucleoplasm; plasma membrane;
Biological process	intracellular signal transduction; phosphorylation; NK T cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; protein phosphorylation; cell adhesion; regulation of cell population proliferation; peptidyl-tyrosine autophosphorylation; protein autophosphorylation; mesoderm development; innate immune response; signal transduction; apoptotic process; phosphatidylinositol biosynthetic process; adaptive immune response; B cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	660
	12169
	ENSG00000102010
	ENSMUSG00000031377
	P51813
	P97504
	NM_001721; NM_203281; NM_001320866
	NM_009759
	NP_001307795; NP_001712; NP_975010
	NP_033889
	Wikidata
View/Edit Human	View/Edit Mouse

PDBOrtholog search: PDBe RCSB

AliasesBMX, ETK, PSCTK2, PSCTK3, BMX non-receptor tyrosine kinase

External IDsOMIM: 300101; MGI: 1101778; HomoloGene: 20411; GeneCards: BMX; OMA:BMX - orthologs

Chr.X chromosome (human)^[1]

Cytoplasmic tyrosine-protein kinase BMX is an enzyme that in humans is encoded by the BMX gene.^[5]^[6]

[1]

[2]

[3]

[4]

[5]

[6]

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

BMX (gene)

Interactions

References

Further reading

External links

Related Articles

Related Articles

"A tyrosine kinase profile of prostate carcinoma"

"Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3′-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells"

"Etk, a Btk Family Tyrosine Kinase, Mediates Cellular Transformation by Linking Src to STAT3 Activation"

"Etk/Bmx as a Tumor Necrosis Factor Receptor Type 2-Specific Kinase: Role in Endothelial Cell Migration and Angiogenesis"

"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"