S1PR4

S1PR4
Identifiers
Aliases	S1PR4, EDG6, LPC1, S1P4, SLP4, sphingosine-1-phosphate receptor 4
External IDs	OMIM: 603751; MGI: 1333809; GeneCards: S1PR4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DCO
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,180,332 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,335,966 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; monocyte; ; spleen; ; bone marrow; ; trabecular bone; ; bone marrow cell; ; lymph node; ; upper lobe of left lung; ; right lung;
	Top expressed in
	granulocyte; ; blood; ; tibiofemoral joint; ; mesenteric lymph nodes; ; spleen; ; bone marrow; ; thymus; ; right lung; ; right lung lobe; ; subcutaneous adipose tissue;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sphingosine-1-phosphate receptor activity; G protein-coupled receptor activity; signal transducer activity; lipid binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; mitochondrion;
Biological process	positive regulation of cytosolic calcium ion concentration; G protein-coupled receptor signaling pathway; adenylate cyclase-activating G protein-coupled receptor signaling pathway; activation of phospholipase C activity; immune response; sphingosine-1-phosphate receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	8698
	13611
	ENSG00000125910
	ENSMUSG00000044199
	O95977
	Q9Z0L1
	NM_003775
	NM_010102
	NP_003766
	NP_034232
	Wikidata
View/Edit Human	View/Edit Mouse

Sphingosine-1-phosphate receptor 4 also known as S1PR4 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P₄.^[5]