SB-216641

SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT_1B, with around 25x selectivity over the closely related 5-HT_1D receptor.^[1] It is used in scientific research,^[2][3][4] and has demonstrated anxiolytic effects in animal studies.^[5][6]

ATC code

• none

CAS Number

• 170230-39-4 ^Y

PubChem CID

• 3292447

IUPHAR/BPS

• 28

Quick facts Clinical data, ATC code ...

SB-216641

Clinical data
ATC code	none
Identifiers
IUPAC name N-[3-[3-(dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide
CAS Number	170230-39-4 Y
PubChem CID	3292447
IUPHAR/BPS	28
ChemSpider	2541153
UNII	ZM4360761C
CompTox Dashboard (EPA)	DTXSID4043985
Chemical and physical data
Formula	C28H30N4O4
Molar mass	486.572 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCOc1cc(ccc1OC)NC(=O)c3ccc(cc3)-c2ccc(cc2C)-c4noc(C)n4
InChI InChI=1S/C28H30N4O4/c1-18-16-22(27-29-19(2)36-31-27)10-12-24(18)20-6-8-21(9-7-20)28(33)30-23-11-13-25(34-5)26(17-23)35-15-14-32(3)4/h6-13,16-17H,14-15H2,1-5H3,(H,30,33) Key:JRNUKVFYILMMLX-UHFFFAOYSA-N
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