SSR-180,575

Chemical compound From Wikipedia, the free encyclopedia

SSR-180,575 is a drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action.[1][2][3][4]

ATC code
  • None
Quick facts Clinical data, ATC code ...
SSR-180,575
Clinical data
ATC code
  • None
Identifiers
  • 7-Chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H19ClN4O2
Molar mass394.86 g·mol−1
3D model (JSmol)
  • Cn2c3cc(Cl)ccc3c1c2c(=O)n(nc1CC(=O)N(C)C)-c4ccccc4
  • InChI=1S/C21H19ClN4O2/c1-24(2)18(27)12-16-19-15-10-9-13(22)11-17(15)25(3)20(19)21(28)26(23-16)14-7-5-4-6-8-14/h4-11H,12H2,1-3H3
  • Key:HJSQVJOROCIILI-UHFFFAOYSA-N
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