Santiago Homenchenko

Homenchenko was born on 30 August 2003 in Mercedes, the capital of Soriano Department. Homenchenko grew up in a working-class family of paternal Ukrainian and maternal Italian descent. The youngest of ten siblings, Homenchenko promised his mother, who was diagnosed with cancer when he was six-years-old, that he would become a professional footballer. In an interview describing his upbringing, Homenchenko said, "We spent nights without eating, relying on milk with rice or sweet cornstarch, but those things give you personality. [...] When I left Danubio at 15, I had to work, because my mother had no money. We were poor, but we weren't sad. I worked to buy my clothes, but we just had what we needed. That confronts you with reality."^[3][4]

Homenchenko began his football career with his neighborhood club Con los Mismos Colores. At the age of 10, he was recruited by Néstor Gonçalves and signed for Peñarol where he finished his childhood training. Homenchenko joined Danubio three years later, moving to Montevideo and beginning his youth training. He was released two years in the process after suffering an accident in which he broke a piece of his heel. During his recovery, he returned to his boyhood club of Con los Mismos Colores under their youth system. After a series of good performances, including winning an under-18 team national championship, he signed with Plaza Colonia for the 2020-21 season.^[5]

In July 2021, Homenchenko returned to Peñarol. On 8 September 2022, he signed his first professional contract with the club.^[4] He made his professional debut on 19 September 2022 as a 84th minute substitute for Brian Lozano in a 3–1 league win over Cerrito.^[6] Homenchenko has also represented the under-19 system, in which he was part of the squad that won the 2022 U-20 Copa Libertadores.^[7][8]

On 15 January 2024, a transfer agreement between Peñarol and Real Oviedo was made for Homenchenko to join the Spanish club, whereas Ecuadorian winger Romario Ibarra, who was playing for Oveido on loan from Pachuca, will join Peñarol. Homenchenko's contract with Peñarol was ending in the middle of the year, therefore the club decided to sell 70% of his contract.^[9][10][11]

On 13 August 2024, Homenchenko moved to fellow Spanish second division side CD Mirandés on a one-year loan deal from Peñarol.^[12] The following 15 January, his loan was cut short.^[13]

After departing Mirandés, Homenchenko joined Mexican side Pachuca.^[14] On 2 August 2025, he joined fellow rival Querétaro on loan for the next season.^[15] He scored his first goal with the club on 23 August, in the 98^th minute of a 3–2 victory against Atlético San Luis.^[16]

Homenchenko has represented Uruguay at various youth levels. In October 2022, he was named in Uruguay's squad for the 2022 South American Games.^[17] He played all five matches in the tournament as Uruguay eventually finished fourth after reaching semi-finals.^[18] He was also part of the Uruguayan side that won the 2023 FIFA U-20 World Cup.^[19][20]

In January 2024, Homenchenko was named in Uruguay's squad for the 2024 CONMEBOL Pre-Olympic Tournament.^[21] In November 2025, he received his first call-up to the Uruguay national team.^[22]

As of 9 March 2026^[2]

Peñarol U20

• U-20 Copa Libertadores: 2022^[23]

Uruguay U20

• FIFA U-20 World Cup: 2023^[19][20]