Simmondsin

Simmondsin is a component of jojoba seeds (pronounced "ho-HO-bah") (Simmondsia chinensis). While it had been considered toxic due to jojoba seed meal causing weight loss in animals, in recent years its appetite suppressant effect has also been researched as a potential treatment for obesity.^[1] It is thought to reduce appetite by increasing levels of cholecystokinin.^[2][3][4][5]

ATC code

• none

CAS Number

• 51771-52-9

PubChem CID

• 6437384

ChemSpider

• 4941947

Quick facts Clinical data, ATC code ...

Simmondsin

Clinical data
ATC code	none
Identifiers
IUPAC name (2Z)-2-[(2S,3R,4S,6R)-2-hydroxy-3,4-dimethoxy-6-[(2R,3R,4S,5S,6R)-3,4,
CAS Number	51771-52-9
PubChem CID	6437384
ChemSpider	4941947
UNII	O51H15R39K
CompTox Dashboard (EPA)	DTXSID901027519
Chemical and physical data
Formula	C16H25NO9
Molar mass	375.374 g·mol−1
3D model (JSmol)	Interactive image
SMILES N#C\C=C2/[C@H](O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)C[C@H](OC)[C@H](OC)[C@H]2O
InChI InChI=1S/C16H25NO9/c1-23-9-5-8(7(3-4-17)11(19)15(9)24-2)25-16-14(22)13(21)12(20)10(6-18)26-16/h3,8-16,18-22H,5-6H2,1-2H3/b7-3+/t8-,9+,10-,11+,12-,13+,14-,15+,16-/m1/s1 Key:KURSRHBVYUACKS-XGYNEUJOSA-N
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