St. Charles, South Carolina

CountryUnited States

Elevation

^[1]

174 ft (53 m)

Time zoneUTC-5 (Eastern (EST))

ZIP Codes

29010 (Bishopville)
29104 (Mayesville)

St. Charles, South Carolina
Census-designated place
Buildings in St. Charles
St. Charles Show map of South Carolina St. Charles Show map of the United States
Coordinates: 34°05′06″N 80°14′15″W / 34.08500°N 80.23750°W / 34.08500; -80.23750[1]
Country	United States
State	South Carolina
County	Lee
Area [2]
• Total	4.24 sq mi (10.97 km2)
• Land	4.24 sq mi (10.97 km2)
• Water	0 sq mi (0.00 km2)
Elevation [1]	174 ft (53 m)
Population  (2020)[3]
• Total	114
• Density	26.9/sq mi (10.39/km2)
Time zone	UTC-5 (Eastern (EST))
• Summer (DST)	UTC-4 (EDT)
ZIP Codes	29010 (Bishopville) 29104 (Mayesville)
Area codes	803/839
FIPS code	45-62485
GNIS feature ID	2807067[1]

St. Charles or Saint Charles^[1] is an unincorporated community and census-designated place (CDP) in Lee County, South Carolina, United States. It was first listed as a CDP prior to the 2020 census^[1] with a population of 114.^[4]

The CDP is in southern Lee County, at the junction of U.S. Route 401 and South Carolina Highway 154. Highway 401 leads northeast 25 miles (40 km) to Darlington and southwest 13 miles (21 km) to Sumter, while Highway 154 leads north 11 miles (18 km) to Bishopville and south 6 miles (10 km) to Mayesville.