Talk:Cell nucleus

I believe the introduction is quite wordy and could be more concise while achieving the same goal.---- — Preceding unsigned comment added by Tristenadams3821 (talk • contribs) 05:18, 29 January 2021 (UTC)

I believe the title should be nucleus, since in biology it is mainly used as in the second form; as a biologist I never came across the phrase "cell nucleus". perhaps, "cellular nucleus", though it is also rare. Araz Zeyniyev (talk) 22:05, 23 December 2022 (UTC)

Under "Structures" is written:"The size of the nucleus depends on the size of the cell it is contained in, with a nucleus typically occupying about 8% of the total cell volume." [Cantwell H, Nurse P (2019). "Unravelling nuclear size control". Current Genetics. Springer. 65 (6): 1282. doi:10.1007/s00294-019-00999-3. PMC 6820586. PMID 31147736.]

This is an excellent citation. I just read it. But the 8% are related to a fission yeast experiment! It is not in all cell types typical, that the nucleus occupies 8% of the cell volume.

Actually, I am working currently with two mammalian cell types. The NC ratio of this cell is about 20%. And these are not abnormal cells I am working with.

In my opinion, I would just delete "with a nucleus typically occupying about 8% of the total cell volume". The rest, inclusive citation, I would leave as it is. Ulmusfagus (talk) 02:08, 1 January 2023 (UTC)

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"IGCs function as storage sites for the splicing factors.[46]" is no longer a supported statement as per new research, see below.

Change to: "Although IGCs were previously thought to be storage sites for splicing factors [46], new genomics technologies have revealed a functional role for nuclear speckles in pre-mRNA splicing. Specifically, nuclear speckles serve as hubs containing high concentrations of splicing factors that diffuse away from the speckles to interact with nascent pre-mRNAs. When a nascent pre-mRNA is located near a nuclear speckle, the volume through which these splicing factors need to diffuse is reduced. This reduction in diffusion volume increases the local concentration of splicing factors around genes positioned near speckles, leading to enhanced spliceosome binding to these pre-mRNAs and more efficient conversion into spliced mRNA [Bhat, P., Chow, A., Emert, B. et al. Genome organization around nuclear speckles drives mRNA splicing efficiency. Nature 629, 1165–1173 (2024). https://doi.org/10.1038/s41586-024-07429-6]." BiologyEditorPerson (talk) 17:24, 2 September 2024 (UTC)

 Already done While the editor didn't include this entire text, the study and its conclusions are mentioned, and more is likely too much for a study this new. PianoDan (talk) 22:02, 23 September 2024 (UTC)

Should probably put a disambiguation / see-also link towards Nucleolus, as they looks quite alike (particularly for new English learners). 海盐沙冰 _{/ aka irisChronomia / Talk} 09:50, 10 November 2025 (UTC)