Talk:Norovirus

I think it would be beneficial to explore the molecular mechanisms of infection in greater detail, specifically the types of receptors necessary for entry and what happens during an immune response to the virus within the host. I think this article also needs to explore the severity of Norovirus infection in nations where clean drinking water is limited. Here are a list of sources that I think could contribute to this new information. Something that could be investigated could be genetic predisposition to infection -- are there certain areas of the world where polymorphisms for cell receptors are more likely to prevent Norovirus infection?

^[1] CDC reports for common outbreak settings

^[2] specifics on the molecular mechanisms for attachment and entry into host cells.

^[3] Explores immune response to human Norovirus based on murine models of the disease. Claims that Norovirus can not be grown in cell culture, which is why they use a mouse model.

^[4] Looking at genetic polymorphisms for cell receptors for many viral infections, of which Norovirus is one of them.

AlveoliRavioli (talk) 22:18, 11 September 2020 (UTC)

The following content was removed as it was based on a primary source:

Serotypes, strains and isolates include:^[1]

• Norwalk virus
• Hawaii virus
• Snow Mountain virus
• Mexico virus
• Desert Shield virus
• Southampton virus
• Lordsdale virus
• Wilkinson virus

I don't know whether any of these viruses are considered strains of norovirus or not. JFW | T@lk 11:41, 15 September 2020 (UTC)

Since there was no definite test, but the doctor thought this virus, how do I track my outbreak back to a source. I have narrowed it down to I think fresh blueberries. 74.192.66.51 (talk) 12:47, 14 January 2022 (UTC)

There is a test: Reverse transcription polymerase chain reaction. Graham Beards (talk) 12:53, 14 January 2022 (UTC)

This WP:PAYWALLED source:

Rübsamen‐Schaeff, Helga; Buschmann, Helmut (2022-01-31). "Antiviral Targets and Strategies to Treat and Prevent Human Norovirus Infections". New Drug Development for Known and Emerging Viruses. Methods and Principles in Medicinal Chemistry (1 ed.). Wiley. doi:10.1002/9783527810697.ch13. ISBN 978-3-527-34337-9.

is available for free from Wiley (publisher) to editors who are eligible for Wikipedia:The Wikipedia Library. To get access:

1. Login with your Wikipedia account at https://wikipedialibrary.wmflabs.org/.
2. Under "My Collections", almost at the end of the page, find the box for Wiley. Click on the blue "Access collection" button.
3. That will take you to the Wiley search page. Put the title of the chapter into the main search box.
4. Click on the matching result, and then download the PDF.

I hope this is useful to you. WhatamIdoing (talk) 20:54, 1 June 2024 (UTC)

Thanks Graham Beards (talk) 05:38, 2 June 2024 (UTC)