Terpene synthase N terminal domain

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Terpene_synth
(+)-bornyl diphosphate synthase: complex with mg and product
Identifiers
SymbolTerpene_synth
PfamPF01397
InterProIPR001906
SCOP25eau / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

In molecular biology, this protein domain belongs to the terpene synthase family (TPS). Its role is to synthesize terpenes, which are part of primary metabolism, such as sterols and carotene, and also part of the secondary metabolism. This entry will focus on the N terminal domain of the TPS protein.

Terpenes synthases have a role in producing important molecules in metabolism, these molecules are part of a large group called terpenoids. In particular, the N terminal domain has feature of the copalyl diphosphate synthase (CPS) active site.[1]

Structure

The N-terminal domain forms an alpha-barrel similar to that of the sesquiterpene cyclase epiaristolochene synthase.[2]

Conservation

See also

References

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