VIP36

VIP36
Identifiers
	IUPAC name methyl (2S)-2-{[6-[4-(diaminomethylideneamino)butoxy]-1-[(4-fluorophenyl)methyl]indazole-3-carbonyl]amino}-3,3-dimethylbutanoate;
PubChem CID	172677805;
Chemical and physical data
Formula	C27H35FN6O4
Molar mass	526.613 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C)[C@@H](C(=O)OC)NC(=O)C1=NN(C2=C1C=CC(=C2)OCCCCN=C(N)N)CC3=CC=C(C=C3)F;
	InChI InChI=1S/C27H35FN6O4/c1-27(2,3)23(25(36)37-4)32-24(35)22-20-12-11-19(38-14-6-5-13-31-26(29)30)15-21(20)34(33-22)16-17-7-9-18(28)10-8-17/h7-12,15,23H,5-6,13-14,16H2,1-4H3,(H,32,35)(H4,29,30,31)/t23-/m1/s1; Key:WMOAPWVQPPIAFY-HSZRJFAPSA-N;

VIP36 is a synthetic cannabinoid derivative, closely related to the highly potent and toxic designer drug MDMB-FUBINACA. However, unlike MDMB-FUBINACA, VIP36 has been substituted with a positively charged guanidine group which prevents it from crossing the blood-brain barrier. As a result, VIP36 is highly peripherally selective and while it produces analgesic effects in animal studies, centrally mediated side effects only became evident at a 100x higher dose.^[1]^[2]

PubChem CID

172677805

FormulaC₂₇H₃₅FN₆O₄

Molar mass526.613 g·mol⁻¹

3D model (JSmol)

Interactive image

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[2]

VIP36

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References

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Identifiers

IUPAC name methyl (2S)-2-{[6-[4-(diaminomethylideneamino)butoxy]-1-[(4-fluorophenyl)methyl]indazole-3-carbonyl]amino}-3,3-dimethylbutanoate
PubChem CID	172677805
Chemical and physical data
Formula	C₂₇H₃₅FN₆O₄
Molar mass	526.613 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)(C)[C@@H](C(=O)OC)NC(=O)C1=NN(C2=C1C=CC(=C2)OCCCCN=C(N)N)CC3=CC=C(C=C3)F
InChI InChI=1S/C27H35FN6O4/c1-27(2,3)23(25(36)37-4)32-24(35)22-20-12-11-19(38-14-6-5-13-31-26(29)30)15-21(20)34(33-22)16-17-7-9-18(28)10-8-17/h7-12,15,23H,5-6,13-14,16H2,1-4H3,(H,32,35)(H4,29,30,31)/t23-/m1/s1 Key:WMOAPWVQPPIAFY-HSZRJFAPSA-N