Volociximab

From Wikipedia, the free encyclopedia

TypeWhole antibody
ATC code
  • none
Volociximab
Monoclonal antibody
TypeWhole antibody
SourceChimeric (mouse/human)
Targetα5β1 integrin
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6434H9942N1706O2040S52
Molar mass145501.33 g·mol−1
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Volociximab (also known as M200) is a chimeric monoclonal antibody jointly developed by PDL BioPharma and Biogen Idec for treatment of a variety of advanced solid tumors. It binds to and inhibits the functional activity of α5β1 integrin.[1]

It is thought to reduce metastases. Early results show potential in renal cell cancers.[citation needed]

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