WDR57

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

WD repeat domain 57 (U5 snRNP specific), also known as WDR57, is a gene found in many organisms, including, but not limited to Homo sapiens, Gallus gallus, Pan troglodytes, Canus familiaris, Bos taurus, Mus musculus, and Rattus norvegicus.[5]

PDBOrtholog search: PDBe RCSB
AliasesSNRNP40, 40K, HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57, small nuclear ribonucleoprotein U5 subunit 40
Quick facts SNRNP40, Available structures ...
SNRNP40
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNRNP40, 40K, HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57, small nuclear ribonucleoprotein U5 subunit 40
External IDsOMIM: 607797; MGI: 1913835; HomoloGene: 3538; GeneCards: SNRNP40; OMA:SNRNP40 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004814

NM_025645

RefSeq (protein)

NP_004805

NP_079921

Location (UCSC)Chr 1: 31.26 – 31.3 MbChr 4: 130.25 – 130.28 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs.[5]

Interactions

WDR57 has been shown to interact with PRPF8[6][7] and EFTUD2.[6][7]

References

Further reading

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