Wikiwand AI

ZFP57

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene.[5]

AliasesZFP57, C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2, ZFP57 zinc finger protein
External IDsOMIM: 612192; MGI: 99204; GeneCards: ZFP57
End29,681,155 bp[1]
Quick facts Identifiers, Aliases ...
ZFP57
Identifiers
AliasesZFP57, C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2, ZFP57 zinc finger protein
External IDsOMIM: 612192; MGI: 99204; GeneCards: ZFP57
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001109809
NM_001366333

NM_001013745
NM_001168501
NM_001168502
NM_009559

RefSeq (protein)

NP_001103279
NP_001353262
NP_001103279.2

NP_001013767
NP_001161973
NP_001161974

Location (UCSC)Chr 6: 29.67 – 29.68 MbChr 17: 37.31 – 37.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor.[5]

Clinical significance

Mutations in the ZFP57 gene may be associated with transient neonatal diabetes mellitus.[6]

References

Further reading

Related Articles

Timelines

Top Qs

Fact Checks