SMARCB1

SMARCB1
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	5AJ1
Identificadores
Alias	SMARCB1, BAF47, INI1, MRD15, PPP1R144, RDT, RTPS1, SNF5, SNF5L1, SWNTS1, Sfh1p, Snr1, hSNFS, CSS3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, INI-1
IDs externos	OMIM: 601607 MGI: 1328366 HomoloGene: 2310 GeneCards: SMARCB1
Enfermedades genéticamente relacionadas
	Coffin-Siris syndrome 3, rhabdoid tumor predisposition syndrome
Ontología génica
Función molecular	• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA binding; • GO:0001187 RNA polymerase I core promoter sequence-specific DNA binding; • GO:0001105 transcription coactivator activity; • p53 binding; • Tat protein binding; • GO:0001948, GO:0016582 unión a proteína plasmática; • nucleosomal DNA binding;
Componente celular	• Nucleoplasma; • nuclear chromosome; • nucléolo; • núcleo celular; • fibrillar center; • intracellular membrane-bounded organelle; • SWI/SNF complex; • npBAF complex; • nBAF complex; • GO:0009327 complejo macromolecular; • brahma complex;
Proceso biológico	• positive regulation of glucose mediated signaling pathway; • Remodelación de la cromatina; • GO:0009373 regulation of transcription, DNA-templated; • DNA integration; • positive regulation of histone H3-K9 acetylation; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II; • positive regulation of transcription of nucleolar large rRNA by RNA polymerase I; • positive regulation of DNA-binding transcription factor activity; • transcription, DNA-templated; • desarrollo neural; • nucleosome disassembly; • positive regulation of histone H4 acetylation; • single stranded viral RNA replication via double stranded DNA intermediate; • ciclo celular; • negative regulation of histone H3-K9 trimethylation; • regulation of histone H4-K16 acetylation; • GO:0022415 proceso viral; • negative regulation of histone H3-K9 dimethylation; • GO:0100026 reparación del ADN; • positive regulation by host of viral transcription; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • negative regulation of cell population proliferation; • diferenciación celular; • RNA polymerase I preinitiation complex assembly; • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization;
	Fuentes: Amigo / QuickGO
Patrón de la expressión del ARN
	Más referencias a datos de expressión
Ortólogos
	6598
	20587
	ENSG00000099956; ENSG00000275837
	ENSMUSG00000000902
	Q12824
	Q9Z0H3
	NM_001007468; NM_003073; NM_001317946; NM_001362877
	NM_001161853; NM_011418
	NP_001007469; NP_001304875; NP_003064; NP_001349806
	NP_001155325; NP_035548
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

SMARCB1 Subunidad B1 del complejo de remodelación de cromatina BAF relacionado con SWI/SNF es una proteína que en humanos está codificada por el gen SMARCB1. Su nombre deriva de las siglas del nombre en inglés: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, es decir, regulador de la cromatina dependiente de actina asociado a la matriz y relacionado con SWI/SNF, miembro 1 de la subfamilia B .^[4]^[5]^[6]

PDBBúsqueda ortóloga: PDBe RCSB

AliasSMARCB1, BAF47, INI1, MRD15, PPP1R144, RDT, RTPS1, SNF5, SNF5L1, SWNTS1, Sfh1p, Snr1, hSNFS, CSS3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, INI-1

IDs externosOMIM: 601607 MGI: 1328366 HomoloGene: 2310 GeneCards: SMARCB1

Función molecular

• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
• DNA binding
• GO:0001187 RNA polymerase I core promoter sequence-specific DNA binding
• GO:0001105 transcription coactivator activity
• p53 binding
• Tat protein binding
• GO:0001948, GO:0016582 unión a proteína plasmática
• nucleosomal DNA binding

Datos rápidos Estructuras disponibles, PDB ...

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SMARCB1

Sinónimos

Función

Interacciones

Referencias

Otras lecturas

Enlaces externos

Related Articles

Related Articles

«Purification and biochemical heterogeneity of the mammalian SWI-SNF complex»

«Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes»

«A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis»