BCL2L11

BCL2L11
	Structure de la protéine BCL2L11. Basée sur l'identifiant PDB 2K7W.
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	1F95, 2K7W, 2NL9, 2V6Q, 2VM6, 2WH6, 2YQ6, 2YQ7, 3D7V, 3FDL, 3IO8, 3IO9, 3KJ0, 3KJ1, 3KJ2, 4A1U, 4A1W, 4B4S, 4D2M, 4QVF, 4UF3, 4YJ4, 4ZIF, 4ZIH, 5AGW, 5AGX, 5C3G
Identifiants
Alias	BCL2L11, Bcl-2-like protein 11, BIM
IDs externes	OMIM: 603827 MGI: 1197519 HomoloGene: 7643 GeneCards: BCL2L11
Position du gène (humain)
Chr.	Chromosome 2 humain
Fin	111,168,445 bp
Position du gène (souris)
Chr.	Chromosome 2 (souris)
Fin	128,004,467 bp
Expression génique
	Fortement exprimé dans
	sperme; ; palpebral conjunctiva; ; epithelium of nasopharynx; ; mucosa of paranasal sinus; ; artère temporale superficielle; ; gingival epithelium; ; monocyte; ; mucosa of colon; ; mucosa of sigmoid colon; ; muqueuse jéjunale;
	Fortement exprimé dans
	transitional epithelium of urinary bladder; ; vestibular membrane of cochlear duct; ; corps ciliaire; ; artère carotide interne; ; épithélium pigmentaire rétinien; ; utricle; ; Rostral migratory stream; ; artère carotide externe; ; sang; ; endothelial cell of lymphatic vessel;
	Plus de données d'expression de référence
	; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison protéique; microtubule binding; dynein complex binding; protein heterodimerization activity; protein kinase binding;
Composant cellulaire	cytoplasme; cytosol; membrane; intracellular membrane-bounded organelle; BIM-BCL-2 complex; membrane mitochondrial externe; BIM-BCL-xl complex; cytoplasmic dynein complex; mitochondrie; microtubule; système endomembranaire; extrinsic component of membrane; Bcl-2 family protein complex;
Processus biologique	leukocyte homeostasis; regulation of apoptotic process; positive regulation of protein homooligomerization; male gonad development; positive regulation of cell death; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; B cell apoptotic process; kidney development; thymus development; lymphocyte homeostasis; positive regulation of apoptotic process by virus; myeloid cell homeostasis; morphogenèse postembryonnaire d'un organe animal; ear development; in utero embryonic development; B cell homeostasis; spleen development; thymocyte apoptotic process; développement postembryonnaire; response to endoplasmic reticulum stress; mammary gland development; T cell homeostasis; odontogenesis of dentin-containing tooth; positive regulation of IRE1-mediated unfolded protein response; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; formation d'un tube; développement cérébral; positive regulation of neuron apoptotic process; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; positive regulation of cell cycle; positive regulation of mitochondrial membrane permeability involved in apoptotic process; meiosis I; spermatogenèse; intrinsic apoptotic signaling pathway in response to DNA damage; extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of apoptotic process; positive regulation of fibroblast apoptotic process; développement d'une pigmentation; positive regulation of release of cytochrome c from mitochondria; regulation of developmental pigmentation; cell-matrix adhesion; regulation of organ growth; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; apoptotic process involved in embryonic digit morphogenesis; apoptose; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; positive regulation of autophagy in response to ER overload; cellular response to glucocorticoid stimulus; cellular response to estradiol stimulus; cellular response to amyloid-beta;
	Sources:Amigo / QuickGO
Orthologues
	10018
	12125
	ENSG00000153094
	ENSMUSG00000027381
	O43521
	O54918
NM_001204106; NM_001204107; NM_001204108; NM_001204109; NM_001204110;
	NM_001204111; NM_001204112; NM_001204113; NM_006538; NM_138621; NM_138622; NM_138623; NM_138624; NM_138625; NM_138626; NM_138627; NM_207002; NM_207003
	NM_001284410; NM_001291016; NM_009754; NM_207680; NM_207681
NP_001191035; NP_001191036; NP_001191037; NP_001191038; NP_001191039;
	NP_001191040; NP_001191041; NP_001191042; NP_006529; NP_619527; NP_619528; NP_619529; NP_619530; NP_619531; NP_619532; NP_619533; NP_996885; NP_996886
NP_001271339; NP_001277945; NP_033884; NP_997563; NP_997564;
	NP_001392986; NP_001392987; NP_001392988; NP_001392989; NP_001392990
	Wikidata
Voir/Editer Humain	Voir/Editer Souris