IDH1

IDH1
	Visualisation de la protéine Cristallisée IDH1
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	1T09, 1T0L, 3INM, 3MAP, 3MAR, 3MAS, 4I3K, 4I3L, 4KZO, 4L03, 4L04, 4L06, 4UMX, 4UMY, 4XRX, 5DE1, 4XS3, 5K10, 5K11
Identifiants
Alias	IDH1
IDs externes	OMIM: 147700 MGI: 96413 HomoloGene: 21195 GeneCards: IDH1
Position du gène (humain)
Chr.	Chromosome 2 humain
Fin	208,266,074 bp
Position du gène (souris)
Chr.	Chromosome 1 (souris)
Fin	65,225,659 bp
Expression génique
	Fortement exprimé dans
	corpus epididymis; ; muqueuse jéjunale; ; right adrenal cortex; ; mucosa of sigmoid colon; ; left adrenal gland; ; left adrenal cortex; ; secondary oocyte; ; duodénum; ; vésicule séminale; ; caput epididymis;
	Fortement exprimé dans
	cumulus cell; ; transitional epithelium of urinary bladder; ; right kidney; ; medial ganglionic eminence; ; left lobe of liver; ; glande surrénale; ; human kidney; ; antre du pylore; ; barrel cortex; ; ganglion cervical supérieur;
	Plus de données d'expression de référence
	n/a
Gene Ontology
Fonction moléculaire	magnesium ion binding; protein homodimerization activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; signaling receptor binding; isocitrate dehydrogenase (NADP+) activity; activité d'oxydoréductase; NAD binding; isocitrate dehydrogenase activity; NADP binding; liaison ion métal; (R)-2-hydroxyglutarate dehydrogenase activity; cadherin binding; identical protein binding;
Composant cellulaire	peroxysome; cytosol; exosome; peroxisomal matrix; cytoplasme; mitochondrie; région extracellulaire; secretory granule lumen; tertiary granule lumen; ficolin-1-rich granule lumen;
Processus biologique	female gonad development; NADPH regeneration; response to oxidative stress; response to organic cyclic compound; response to steroid hormone; 2-oxoglutarate metabolic process; regulation of phospholipid catabolic process; isocitrate metabolic process; cycle du glyoxylate; cycle de Krebs; regulation of phospholipid biosynthetic process; glutathione metabolic process; neutrophil degranulation; protein targeting to peroxisome; NADP metabolic process;
	Sources:Amigo / QuickGO
Orthologues
	3417
	15926
	ENSG00000138413
	ENSMUSG00000025950
	O75874
	O88844
	NM_005896; NM_001282386; NM_001282387
	NM_001111320; NM_010497
	NP_001269315; NP_001269316; NP_005887
	NP_001104790; NP_034627
	Wikidata
Voir/Editer Humain	Voir/Editer Souris