MYCN

MYCN
	Structure de la protéine proto-oncogène N-myc (MYCN)
Identifiants
Alias	MYCN
IDs externes	OMIM: 164840 MGI: 97357 HomoloGene: 3922 GeneCards: MYCN
Position du gène (humain)
Chr.	Chromosome 2 humain
Fin	15,947,007 bp
Position du gène (souris)
Chr.	Chromosome 12 (souris)
Fin	12,991,915 bp
Expression génique
	Fortement exprimé dans
	ventricular zone; ; embryon; ; éminence ganglionnaire; ; gonade; ; placenta; ; tubule rénal; ; testicule; ; gyrus temporal moyen; ; Caduque basale; ; Brodmann area 23;
	Fortement exprimé dans
	ligne primitive; ; épiblaste; ; follicule pileux; ; medial ganglionic eminence; ; somite; ; ventricular zone; ; paroi abdominale; ; mandibular prominence; ; maxillary prominence; ; ganglion cervical supérieur;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison ADN; protein dimerization activity; DNA-binding transcription factor activity; liaison protéique; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; liaison de kinase; DNA-binding transcription factor activity, RNA polymerase II-specific;
Composant cellulaire	chromatine; noyau; nucléole;
Processus biologique	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of gene expression; negative regulation of gene expression; positive regulation of production of miRNAs involved in gene silencing by miRNA; transcription by RNA polymerase II; cartilage condensation; positive regulation of mesenchymal cell proliferation; positive regulation of cell population proliferation; positive regulation of cell death; développement des poumons; embryonic digit morphogenesis; regulation of inner ear auditory receptor cell differentiation; régulation positive de la transcription dépendante de l'ADN; positive regulation of transcription by RNA polymerase II; embryonic skeletal system morphogenesis; negative regulation of astrocyte differentiation; branching morphogenesis of an epithelial tube; negative regulation of reactive oxygen species metabolic process;
	Sources:Amigo / QuickGO
Orthologues
	4613
	18109
	ENSG00000134323
	ENSMUSG00000037169
	P04198
	P03966
	NM_005378; NM_001293228; NM_001293231; NM_001293233
	NM_008709
	NP_001280157; NP_001280160; NP_001280162; NP_005369
	NP_032735
	Wikidata
Voir/Editer Humain	Voir/Editer Souris