NOX4

NOX4
Identifiants
Alias	NOX4
IDs externes	OMIM: 605261 MGI: 1354184 HomoloGene: 41065 GeneCards: NOX4
Position du gène (humain)
Chr.	Chromosome 11 humain
Fin	89,498,187 bp
Position du gène (souris)
Chr.	Chromosome 7 (souris)
Fin	87,047,918 bp
Expression génique
	Fortement exprimé dans
	tendon calcanéen; ; tubule rénal; ; glomérule rénal; ; metanephric glomerulus; ; aorte ascendante; ; human kidney; ; Descending thoracic aorta; ; péricarde; ; artère poplitée; ; Tibial arteries;
	Fortement exprimé dans
	human kidney; ; tunica media of zone of aorta; ; right kidney; ; lumbar spinal ganglion; ; epithelium of small intestine; ; left lobe of liver; ; aorte ascendante; ; corpuscule carotidien; ; valve aortique; ; renal cortex;
	Plus de données d'expression de référence
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison nucléotide; NAD(P)H oxidase H2O2-forming activity; flavin adenine dinucleotide binding; oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; liaison d'acide aminé modifié; liaison protéique; heme binding; electron transfer activity; activité d'oxydoréductase; oxygen gasoreceptor activity; superoxide-generating NAD(P)H oxidase activity; protein tyrosine kinase binding;
Composant cellulaire	integral component of membrane; membrane; focal adhesion; membrane plasmique; stress fiber; jonction cellulaire; NADPH oxydase; nucléole; apical plasma membrane; mitochondrie; réticulum endoplasmique; perinuclear region of cytoplasm; périphérie d'une cellule; membrane du réticulum endoplasmique; noyau; perinuclear endoplasmic reticulum;
Processus biologique	cellular response to transforming growth factor beta stimulus; positive regulation of protein kinase B signaling; response to hypoxia; expression génétique; positive regulation of MAP kinase activity; cardiac muscle cell differentiation; vieillissement; résorption osseuse; reactive oxygen species metabolic process; superoxide anion generation; positive regulation of smooth muscle cell migration; positive regulation of reactive oxygen species metabolic process; cellular response to gamma radiation; cell morphogenesis; positive regulation of DNA biosynthetic process; positive regulation of ERK1 and ERK2 cascade; positive regulation of apoptotic process; homocysteine metabolic process; réponse inflammatoire; positive regulation of stress fiber assembly; cellular response to cAMP; cellular response to glucose stimulus; superoxide metabolic process; negative regulation of cell population proliferation; cellular response to oxidative stress; chaîne de transport d'électrons; heart process; positive regulation of protein tyrosine kinase activity; reactive oxygen species biosynthetic process; réponse de défense;
	Sources:Amigo / QuickGO
Orthologues
	50507
	50490
	ENSG00000086991
	ENSMUSG00000030562
	Q9NPH5
	Q9JHI8
NM_001143836; NM_001143837; NM_001291926; NM_001291927; NM_001291929;
	NM_001300995; NM_016931
	NM_001285833; NM_001285835; NM_015760
NP_001137308; NP_001137309; NP_001278855; NP_001278856; NP_001278858;
	NP_001287924; NP_058627
	NP_001272762; NP_001272764; NP_056575
	Wikidata
Voir/Editer Humain	Voir/Editer Souris