2016 Las Vegas Challenger

Country	Player	Rank1	Seed
DOM	Víctor Estrella Burgos	83	1
USA	Frances Tiafoe	100	2
USA	Bjorn Fratangelo	112	3
COL	Santiago Giraldo	124	4
BAR	Darian King	130	5
USA	Denis Kudla	147	6
USA	Dennis Novikov	148	7
ARG	Marco Trungelliti	152	8

• ¹ Rankings are as of October 10, 2016.

The following players received wildcards into the singles main draw:

• Jakob Amilon
• Alejandro Falla
• Evan Song
• Mikael Torpegaard

The following player received entry into the singles main draw as a special exempt:

• Brydan Klein

The following players received entry from the qualifying draw:

• Liam Broady
• Salvatore Caruso
• Lloyd Glasspool
• Roberto Ortega Olmedo

The following player entered as a lucky loser:

• Tucker Vorster

• Sam Groth def. Santiago Giraldo, 6–7^(4–7), 6–4, 7–5^[1]

• Brian Baker / Matt Reid def. Bjorn Fratangelo / Denis Kudla, 6–1, 7–5.