2C-T-3

Pharmaceutical compound From Wikipedia, the free encyclopedia

2C-T-3, also initially numbered as 2C-T-20 and also known as 4-methallylthio-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-16. It was named by Alexander Shulgin but was never made or tested by him, and was instead first synthesised by Daniel Trachsel some years later. It has a binding affinity of 11nM at 5-HT2A and 40nM at 5-HT2C. It is reportedly a potent psychedelic drug with an active dose in the 15–40 mg range, and a duration of action of 8–14 hours, with visual effects comparable to related drugs such as methallylescaline.[2][3][1] 2C-T-3 is a controlled substance in Canada under phenethylamine blanket-ban language.[4]

Other names2C-T-20; 4-Methallylthio-2,5-dimethoxyphenethylamine
Routes of
administrationOral[1]
Drug classSerotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Quick facts Clinical data, Other names ...
2C-T-3
Clinical data
Other names2C-T-20; 4-Methallylthio-2,5-dimethoxyphenethylamine
Routes of
administration		Oral[1]
Drug classSerotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action8–14 hours[1]
Identifiers
  • 2-{2,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)sulfanyl]phenyl}ethan-1-amine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H21NO2S
Molar mass267.39 g·mol−1
3D model (JSmol)
  • CC(=C)CSC1=C(C=C(C(=C1)OC)CCN)OC
  • InChI=1S/C14H21NO2S/c1-10(2)9-18-14-8-12(16-3)11(5-6-15)7-13(14)17-4/h7-8H,1,5-6,9,15H2,2-4H3
  • Key:JCDUUDQZKIXJJP-UHFFFAOYSA-N
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