3-Phenylpiperidine

Pharmaceutical compound From Wikipedia, the free encyclopedia

3-Phenylpiperidine is a chemical compound and cyclized phenethylamine.[1] It can be thought of as β-phenethylamine with a propyl group connecting the amine and the β position.[1]

ATC code
  • None
Quick facts Clinical data, ATC code ...
3-Phenylpiperidine
Clinical data
ATC code
  • None
Identifiers
  • 3-phenylpiperidine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.021.458 Edit this at Wikidata
Chemical and physical data
FormulaC11H15N
Molar mass161.248 g·mol−1
3D model (JSmol)
  • C1CC(CNC1)C2=CC=CC=C2
  • InChI=1S/C11H15N/c1-2-5-10(6-3-1)11-7-4-8-12-9-11/h1-3,5-6,11-12H,4,7-9H2
  • Key:NZYBILDYPCVNMU-UHFFFAOYSA-N
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According to Daniel Trachsel and colleagues in 2013, the pharmacology of 3-phenylpiperidine itself has not been reported, only its chemical synthesis has been described.[1][2] 3-Phenylpiperidine was first described in the scientific literature by 1933.[1][2]

Derivatives

3-Phenylpiperidine is a parent compound of several drugs such as the psychedelic and related drugs LPH-5 ((S)-2C-TFM-3PIP),[3] 2C-B-3PIP, 2C-B-3PIP-NBOMe, 2C-B-3PIP-POMe, 2T-2CTFM-3PIP, and Z3517967757 (Z7757),[4] the antipsychotic OSU-6162,[5] and the sigma receptor agonist 3-PPP.[1]

Chemical structures of selected 3-phenylpiperidines

See also

References

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